Telomere damage, epigenetic dysregulation, DNA damage, and mitochondrial dysfunction are primary drivers of damage in aging. Several of these drivers of damage can induce senescence. Senescence can in turn drive the consequential aging hallmarks in response to damage: stem cell exhaustion and chronic inflammation.
Similarly, is aging a peer-reviewed journal?
Aging is a bimonthly peer–reviewed open access bio-medical journal covering research on all aspects of gerontology. The journal was established in 2009 and is published by Impact Journals. The editors-in-chief are Jan Vijg, David Andrew Sinclair, Vera Gorbunova, Judith Campisi, Mikhail V.
Consequently, how does cell division affect stress and aging? But cell division is not limitless: on average, human cells can divide only about 50 to 70 times. Afterwards, cells will enter a senescence phase when they no longer divide. At this point, the cells may die, or stay in the body as malfunctioning cells. This causes our bodies to deteriorate and age.